Transmission of Hepatitis C Virus: Rates, Routes, and Cofactors

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Transmission of hepatitis C virus: rates, routes, and cofactors.

The existence of a viral cause of hepatitis other than hepatitis A and hepatitis B was first recognized in the early 1970s following the development of diagnostic blood tests for hepatitis A and hepatitis B. Early studies showed that appreciable proportions of people presenting with acute hepatitis following blood transfusion or community-acquired hepatitis did not have any serologic evidence o...

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Routes of transmission of hepatitis C virus.

Hepatitis C is one of the most common causes of chronic liver disease in Latin America. It is essential to understand the different mechanisms of transmission of the infection in order to design control measures. The pattern of transmission of the infection in our region suggests that the peak of the infection occurred 30 to 50 years ago. While most infections in Latin America seem to be the re...

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Transmission routes of hepatitis C virus infection

The definitive identification of the hepatitis C genome in 1989 resulted in confirmation that this virus is a worldwide health problem.(1) The hepatitis C virus (HCV) is one of the most common causes of chronic liver disease and is one of the principal indications for liver transplantation. It is estimated that about four million Americans harbor hepatitis C antibodies. The virus is present in ...

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Risk of Hepatitis C Virus transmission Following Upper Gastrointestinal Endoscopy

Background: Hepatitis C virus infection (HCV) is a main health problem in our country. It is thought that the transmission of hepatitis C virus (HCV) through the endoscopic procedures is a rare event. The aim of this study was to evaluate the risk of conventional disinfection in the transmission of HCV. Materials and methods: A prospective study, comprising 456 consecutive upper gastrointestin...

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Cellular cofactors affecting hepatitis C virus infection and replication.

Recently identified hepatitis C virus (HCV) isolates that are infectious in cell culture provide a genetic system to evaluate the significance of virus-host interactions for HCV replication. We have completed a systematic RNAi screen wherein siRNAs were designed that target 62 host genes encoding proteins that physically interact with HCV RNA or proteins or belong to cellular pathways thought t...

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ژورنال

عنوان ژورنال: Epidemiologic Reviews

سال: 1996

ISSN: 0193-936X,1478-6729

DOI: 10.1093/oxfordjournals.epirev.a017921